Morin & Its Derivatives

Morin - Bioflavonoid Properties, Uses and Benefits

Learn about Morin, a bioflavonoid with anti-inflammatory, antioxidant, and anticancer properties. Discover its uses in textile dyeing, analytical chemistry, and more. Find out why Morin is used to treat various diseases.

Morin - Bioflavonoid Properties, Uses and Benefits

Discover its uses in textile dyeing, analytical chemistry and more...

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Product Description and Applications

Morin (M3735) and Morin hydrate (2′,3,4′,5,7-Pentahydroxyflavone, CAS 480-16-0 resp. CAS 654055-01-3) is a bioflavonoid mainly obtained from fruits, stem, and leaves of Moraceae family members’ plants.1 The yellow-beige chemical compound can be isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic), and from leaves of Psidium guajava (common guava).2, 6 Other names are: Aurantica, Calico Yellow, Toxylon pomiferum and Bois d’arc.

Morin has been described to have a wide range of pharmacological properties, including anti-inflammatory, antioxidant, free radical scavenging in various diseases like cancer, acute lung injury, liver injury, neuroinflammatory disorders, nephrotoxicity, diabetes, gastritis, mastitis, and myocardial infarction. 1

Flavonoids such as Morin are the most significant natural antioxidants with intense anti-cancer action under both in-vivo and in-vitro conditions. 3, 4

Since the beginning of industrialization, Morin has been used as the best yellow dye for cotton, wool, and silk. For this purpose, the goods to be dyed were first pretreated with metal salts. Various colors could be achieved by reacting Morin with the metal ions. Morin produces olive-green colors with iron salts, brown-yellow with copper salts, and yellow with lead and tin salts.5

In analytical chemistry Morin (M3735) is used for fluorometric detection experiments for various metal ions like aluminum, beryllium, gallium, indium, scandium, titanium and tin.5

From US Patent 5492615 and DE Patent 1009380 also the use of flavonoles for the electrolytic deposition of tin layers is known.

Benefits / USP

  • Despite its large potential and use in industrial scale, Morin is still only available after extraction from a very slow growing tropical tree (mainly Maclura tinctoria or Dyer’s Mulberry), to be found only in the neotropics, making Morin expensive and ecologically unsustainable. European Union will limit the import of products from unsutainable sources end of 2026. EU rules to guarantee that the products EU citizens consume do not contribute to deforestation or forest degradation worldwide.8
  • The Morin quality, currently used on the market on a kilogram scale has so far been extracted from tropical timber and is offered in a strongly varying purity between 65% and 85% (m/m).
  • ORSAtec is addressing the problem of erratic purity thanks to its patented chemical synthesis 7 of Morin (US-11312696-B2, EP4169911A1).
  • Thanks to the HPLC controlled purity and high concentration (≥ 95% (m/m)) of ORSAtec´s Morin product it works much better and more predictably than the natural compound.

Packaging and Pricing

ORSAtec´s Morin ((M3735) , CAS 480-16-0, ≥ 95.0 % purity) is available in different pack sizes:

Amount Price
1 gram 35,00 €
5 gram 50,00 €
25 gram 225,00 €
1000 gram 3.850,00 €

For bulk volumes please request your personal quote. HS codes for Morin and Morin extracts: 2932 99 00, 3203 0010, 3204 1399.

Safety data sheet, Certificate of Analysis and NMR

SDS download

Safety Data Sheet

CoA download

Certificate of Analysis

1H & 13C NMR download

NMR Spectra

Citations:

  1. Shahid Ali Rajput, Xiu-qi Wang, Hui-Chao Yan, Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential, Biomedicine & Pharmacotherapy, Vol. 138, 2021, 111511.
  2. Rattanachaikunsopon, Pongsak; Phumkhachorn, Parichat (2007). “Bacteriostatic effect of flavonoids isolated from leaves of Psidium guajava on fish pathogens”. Fitoterapia. 78 (6): 434–436. doi:10.1016/j.fitote.2007.03.015. PMID 17553634.
  3. V. Sivaramakrishnan, P.N.M. Shilpa, V.R.P. Kumar, S.N. Devaraj: Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin, Chem. Biol. Interact., 171 (1) (2008), pp. 79-88.
  4. Q. Zhang, F. Zhang, K. Thakur, J. Wang, H. Wang, F. Hu, J.-G. Zhang, Z.-J. Wie, Molecular mechanism of anti-cancerous potential of Morin extracted from mulberry in Hela cells, Food Chem. Toxicol., 112 (2018), pp. 466-475.
  5. https://de.wikipedia.org/wiki/Morin_(Farbstoff)
  6. Shekhar Kumar, Akanksha Raghuvanshi, Aman Kumar, Vikramdeep Monga, Morin: A Comprehensive Review of Its Sources, Nutraceutical Prospects, Chemistry, and Pharma-cological Insights, Phytotherapy Research, 2026; 0:1–41.
  7. Grigor Gurzadyan, Steffen Mende, Alexander Schmid, Thomas Lindel, Multigram, Chromatography-Free Synthesis of the Flavonol Morin, Org. Process Res. Dev. 2023, 27, 890−898.
  8. https://environment.ec.europa.eu/topics/forests/deforestation/regulation-deforestation-free-products_en